Spherical Viruses
نویسنده
چکیده
Electron microscopy and X-ray scattering show that double-stranded DNA is wound in a regular way in the heads of phage such as p22 and ).. DNA is "pumped" into such heads, which may simply act as passive containers. In contrast, the protein-coat subunits of tomato bushy stunt virus have a flexibly tethered N-terminal domain that appears to be a major locus of interactions with the compactly folded RNA. Both modes of packaging permit considerable latitude in the detailed arrangernent of the nucleic-acid chain, while still ensuring specific and efficient incorporation.
منابع مشابه
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We have found that small-angle X-ray solution scattering from spherical viruses may sometimes give information about surface organization. Experinaental data for two viruses (wild cucumber mosaic virus and polyoma virus) are ~nalysed, and it is shown that in each case the differences between the observed scattering curve and that expected from a solid sphere of uniform density may be accounted ...
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